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Orphan nuclear receptors as regulators of intratumoral androgen  biosynthesis in castration-resistant prostate cancer | Oncogene
Orphan nuclear receptors as regulators of intratumoral androgen biosynthesis in castration-resistant prostate cancer | Oncogene

Targeting signaling pathways in prostate cancer: mechanisms and clinical  trials | Signal Transduction and Targeted Therapy
Targeting signaling pathways in prostate cancer: mechanisms and clinical trials | Signal Transduction and Targeted Therapy

CYP17 inhibitors for prostate cancer therapy - ScienceDirect
CYP17 inhibitors for prostate cancer therapy - ScienceDirect

Biased cytochrome P450-mediated metabolism via small-molecule ligands  binding P450 oxidoreductase | Nature Communications
Biased cytochrome P450-mediated metabolism via small-molecule ligands binding P450 oxidoreductase | Nature Communications

APExBIO - Abiraterone|Potent CYP17 inhibitor|CAS# 154229-19-3
APExBIO - Abiraterone|Potent CYP17 inhibitor|CAS# 154229-19-3

APExBIO - TOK-001|CYP17 inhibitor and androgen receptor (AR)  antagonist|CAS# 851983-85-2
APExBIO - TOK-001|CYP17 inhibitor and androgen receptor (AR) antagonist|CAS# 851983-85-2

CYP17 inhibition as a hormonal strategy for prostate cancer | Nature  Reviews Urology
CYP17 inhibition as a hormonal strategy for prostate cancer | Nature Reviews Urology

Mechanisms of resistance to CYP17 inhibitors. Androgen receptor (AR)... |  Download Scientific Diagram
Mechanisms of resistance to CYP17 inhibitors. Androgen receptor (AR)... | Download Scientific Diagram

Cardiovascular Effects of Androgen Deprivation Therapy in Prostate Cancer:  Contemporary Meta-Analyses | Arteriosclerosis, Thrombosis, and Vascular  Biology
Cardiovascular Effects of Androgen Deprivation Therapy in Prostate Cancer: Contemporary Meta-Analyses | Arteriosclerosis, Thrombosis, and Vascular Biology

Frontiers | Second-Generation Antiandrogens: From Discovery to Standard of  Care in Castration Resistant Prostate Cancer
Frontiers | Second-Generation Antiandrogens: From Discovery to Standard of Care in Castration Resistant Prostate Cancer

CYP17 inhibitors in prostate cancer: latest evidence and clinical potential  - Anitha B. Alex, Sumanta K. Pal, Neeraj Agarwal, 2016
CYP17 inhibitors in prostate cancer: latest evidence and clinical potential - Anitha B. Alex, Sumanta K. Pal, Neeraj Agarwal, 2016

CYP17 inhibitors—abiraterone, C17,20-lyase inhibitors and multi-targeting  agents | Nature Reviews Urology
CYP17 inhibitors—abiraterone, C17,20-lyase inhibitors and multi-targeting agents | Nature Reviews Urology

Drug discovery in advanced prostate cancer: translating biology into  therapy | Nature Reviews Drug Discovery
Drug discovery in advanced prostate cancer: translating biology into therapy | Nature Reviews Drug Discovery

CYP17 blockade by abiraterone: further evidence for frequent continued  hormone-dependence in castration-resistant prostate cancer | British  Journal of Cancer
CYP17 blockade by abiraterone: further evidence for frequent continued hormone-dependence in castration-resistant prostate cancer | British Journal of Cancer

CYP17 inhibitors for prostate cancer therapy - ScienceDirect
CYP17 inhibitors for prostate cancer therapy - ScienceDirect

Molecules | Free Full-Text | Enzyme Activity of Natural Products on Cytochrome  P450
Molecules | Free Full-Text | Enzyme Activity of Natural Products on Cytochrome P450

CYP17 inhibitors—abiraterone, C17,20-lyase inhibitors and multi-targeting  agents | Nature Reviews Urology
CYP17 inhibitors—abiraterone, C17,20-lyase inhibitors and multi-targeting agents | Nature Reviews Urology

Androgen-targeted therapy in men with prostate cancer: evolving practice  and future considerations | Prostate Cancer and Prostatic Diseases
Androgen-targeted therapy in men with prostate cancer: evolving practice and future considerations | Prostate Cancer and Prostatic Diseases

The influence of steroid metabolism on CYP17A1 inhibitor activity | Nature  Reviews Urology
The influence of steroid metabolism on CYP17A1 inhibitor activity | Nature Reviews Urology

Resistance to second-generation androgen receptor antagonists in prostate  cancer | Nature Reviews Urology
Resistance to second-generation androgen receptor antagonists in prostate cancer | Nature Reviews Urology

CYP17 inhibitors for prostate cancer therapy - ScienceDirect
CYP17 inhibitors for prostate cancer therapy - ScienceDirect

Computation | Free Full-Text | Exploring the Chemical Space of Cytochrome  P450 Inhibitors Using Integrated Physicochemical Parameters, Drug  Efficiency Metrics and Decision Tree Models
Computation | Free Full-Text | Exploring the Chemical Space of Cytochrome P450 Inhibitors Using Integrated Physicochemical Parameters, Drug Efficiency Metrics and Decision Tree Models

Structures of cytochrome P450 17A1 with prostate cancer drugs abiraterone  and TOK-001 | Nature
Structures of cytochrome P450 17A1 with prostate cancer drugs abiraterone and TOK-001 | Nature

ARe we there yet? Understanding androgen receptor signaling in breast  cancer | npj Breast Cancer
ARe we there yet? Understanding androgen receptor signaling in breast cancer | npj Breast Cancer

Promising Tools in Prostate Cancer Research: Selective Non-Steroidal Cytochrome  P450 17A1 Inhibitors | Scientific Reports
Promising Tools in Prostate Cancer Research: Selective Non-Steroidal Cytochrome P450 17A1 Inhibitors | Scientific Reports